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長庚大學臨床資訊與醫學統計研究中心

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108年4月2日(二)辦理演講「Genome-wide association study identifies a functional variant at 1q24.2 associated with breast cancer survival by promoting cancer immunity」,歡迎踴躍參加。

一、活動時間:108年4月2日 (二) 12:00~13:30
二、活動地點:第二醫學大樓B1會議廳三
三、題目:Genome-wide association study identifies a functional variant at 1q24.2 associated with breast cancer survival by promoting cancer immunity.
四、主講人:沈志陽 教授
台灣流行病學會 理事長
中央研究院 生物醫學科學研究所 特聘研究員/教授
北卡羅來納州立大學 博士(Major: Epidemiology/Cancer/Infectious Diseases)
五、摘要:
A GWAS for breast cancer survival was conducted, and identified 25 significant loci (P<1 x 10-5). After variants imputation and integrated analyses, one SNP located in 1q24.2 was found being a causal variant for breast cancer progression. A series of experiments were performed to demonstrate transcription factor MYBL2 was able to discriminately bind at specific allele to promote XCL1 expression in breast cancer cells. Since XCL1 was known as a chemokine to attract type 1 dendritic cells to tumor microenvironment, we observed in breast cancer tissues that higher XCL1 expression is correlated with higher DC1 signatures and contributed to better prognosis.
六、聯絡人:臨床資訊與醫學統計研究中心 邱小姐 分機:3760
七、報名方式:請登入校務資訊系統中的「提升教學品質研討會報名系統」報名,無法報名者請來信: zi@mail.cgu.edu.tw,主旨請註明「報名4/2演講」並留下您的單位、大名、職稱,名額限99人,請盡早報名,謝謝!
八、報名日期截止:108年4月1日(一)。
九、主辦單位:臨床資訊與醫學統計研究中心
十、注意事項:
1.請教師衡酌時間,確認可全程參與再報名並準時出席,逾報到時間20分鐘恕不給予簽到。
2.為了對演講者表示尊重,及避免違反學術倫理行為,請全程參加並於會後簽退,未完成簽退者,本次專題演講將無法納入教師成長時數。
備註:現場備有茶點。
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