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陳冠甫臨床助理教授
1.姓名:陳冠甫
2.工作單位:基隆長庚醫院/長庚大學
3.職稱:主治醫師/助理教授/醫師研究員
4.科別:
【醫院】急診醫學科
【大學】臨床資訊與醫學統計研究中心
5.聯絡地址:333桃園市龜山區復興街五號
6.連絡電話:(03)328-1200#3531
7.電子信箱:kfchen@cgmh.org.tw
8.個人網站:http://cims.cgu.edu.tw/files/15-1079-24660,c4463-1.php
https://www.facebook.com/drkfchen

9.研究領域:
重症醫學
急診醫學
感染醫學
一般醫學
公共衛生及環境醫學
醫學統計
臨床試驗
系統性回顧及統合分析

10.工作經歷:
現職基隆長庚紀念醫院急診醫學科主治醫師
長庚紀念醫院醫師研究員
美國約翰霍普金斯大學急診醫學部修研醫師(95年3月~99年9月)
美國匹茲堡大學參訪醫師
加拿大亞伯達大學參訪醫師
美國阿拉巴馬大學參訪醫師

11.學歷:
中山醫學大學醫學系學士
約翰霍普金斯大學臨床醫學博士

12.殊榮(獲獎消息):無

13.代表論文(至多5篇):

14.專利(請依以下格式填寫):無

15.學會或專業認證:無

16.目前進行中研究計畫的計劃名:

*社區醫學世代研究中心-世代社區醫學研究檢體核心單位
*腦中風合併脫水的病人,以血液尿素氮/肌酐酸比值為基礎的輸液治療,對降低神經惡化率及改善短期功能預後的影響
*美國及台灣健康照顧中心之人類流行性感冒監測
*針對社區肺炎引起及併發症及死亡探討:宿主生理指標、菌種及預後的相關性
*使用機器學習及訊號處理理論整合感染症病患的生理訊號、自律神經失衡、 傳統及新穎的炎症生物標記、來發展及驗證早期預估治療效果的臨床預測模型:一個敗血症生物標誌在急診的醫院世代研究

17.所有發表期刊論文:

1. Lin, CC; Chen, KF; Shih, CP; Seak, CJ; Hsu, KH. The prognostic factors of hypotension after rapid sequence intubation. Am J Emerg Med. 2008 Oct;26(8):845-51.

2. Chen, KF; Gaydos, CA; Rothman, RE. Update on emerging infections: news from the Centers for Disease Control and Prevention. Hospitalized patients with novel influenza A (H1N1) virus infection--California, April-May, 2009.Ann Emerg Med. 2009 Nov;54(5):732-6

3. Hsieh, YH; Chen, KF; Gaydos, CA; Rothman, RE; Kelen, GD. Antiviral Prescriptions to U.S. Ambulatory Care Visits with a Diagnosis of Influenza before and after High Level of Adamantane Resistance 2005–06 Season. PLoS One. 2010 Jan 28;5(1):e8945.

4. Chen KF. Evaluation of a potential novel biomarker & derivation of clinical prediction rules for severe influenza in emergency department patients. Baltimore: Johns Hopkins University; 2010.

5. Chen, KF; Blyn, L; Rothman, RE; Ramachandran, P; Valsamakis, A; Ecker, D; Sampath, R; Gaydos, CA. RT-PCR and Electrospray Ionization Mass Spectrometry (RT-PCR/ESI-MS) for Identifying Acute Viral Upper Respiratory Tract Infections. Diagnostic Microbiology and Infectious Disease. 2011 Feb;69(2):179-86

6. Chen, KF; Rothman, RE; Ramachandran, P; Blyn, L; Sampath, R; Valsamakis, A; Gaydos, CA. Rapid Identification Viruses from Nasal Pharyngeal Aspirates in Acute Viral Respiratory Infections by RT-PCR and Electrospray Ionization Mass Spectrometry (RT-PCR/ESI-MS). Journal of Virological Methods. 2011 Apr;173(1):60-6.

7. Shih, TY; Chen, KF (co-first author); Rothman, RE; Hsieh, YH. U.S. National Estimation of Emergency Department Utilization of Patients Given “HIV/AIDS related illness” as Their Primary Diagnosis. HIV Med. 2011 Jul;12(6):343-51.

8. Chen, KF; Colantuoni, E; Siddiqi F; Dinglas VD; Sepulveda KA; Fan E, Pronovost P; Needham DM. Repeated attempts using different strategies are important for timely contact with study participants. Journal of Clinical Epidemiology. 2011 Oct;64(10):1144-51

9. Yu, JH; Weng, YM; Chen, KF (co-first author); Chen, SY; Lin, CC. Triage vital signs predict in-hospital mortality among emergency department patients with acute poisoning: a case control study. BMC Health Serv Res. 2012 Aug 18;12:262.

10. Chiu, MT; Chen, CM*; Lin, CC; Li, CH; Chaou, CH; Chen, HY; Chen, KF. Evaluation of the association between postintubation hypotension and lidocaine administered as a premedication for rapid sequence intubation: A comparison between traditional regression methods and propensity score matching-based method. Journal of Acute Medicine, 2013 Feb; 33-38.

11. Chen, KF; Hsieh, YH; Gaydos, CA; Valsamakis, A; Rothman, RE. Derivation of a Clinical Prediction Rule to Predict Hospitalization for Influenza in Emergency Departments. Am J Emerg Med, 2013 Mar;31(3):529-34

12. Hsieh, YH; Kelen, GD; Duglas, AF; Chen, KF; Rothman, RE. Emergency Physician’s Adherence to Center for Disease Control and Prevention Guidance During the 2009 Influenza A H1N1 Pandemic. West J Emerg Med. 2013 Mar; 14(2):191-9.

13. Lynn JJ, Chen KF, Weng YM, Chiu TF. Risk factors associated with complications in patients with chemotherapy-induced febrile neutropenia in emergency department. Hematol Oncol. 2013 Dec; 31(4):189-96.

14. Schreiber MP, Colantuoni E, Bienvenu OJ, Neufeld KJ, Chen KF, Shanholtz C, Mendez-Tellez PA, Needham DM. Corticosteroids and transition to delirium in patients with acute lung injury. Crit Care Med. 2014 Jun;42(6):1480-6.

15. Brown, QL; Linton, SL; Harrell, PT; Mancha, BE; Alexandre, PK.; Chen, KF; Eaton, WW. The Influence of Religious Attendance on Smoking. Subst Use Misuse. 2014 Sep;49(11):1392-9.

16. Yeh, CF; Chen, KF; Ye, JJ; Huang, CT. Derivation of a clinical prediction rule for bloodstream infection mortality of patients visiting the emergency department based on predisposition, infection, response and organ dysfunction concept. J Microbiol Immunol Infect. 2014 Dec;47(6):469-77.

17. Tseng JC, Li CH, Chen KF, Chan YL, Chang SS, Wang FL, Chiu TF, Chen JC. Outcomes of an emergency department intensive care unit in a tertiary medical center in Taiwan: An observational study. J Crit Care. 2015 Jun;30(3):444-8.

18. Lei, KF; Huang, CH; Kuo, RL; Chang CK; Chen, KF; Tsao KC; Tsang, NM. Paper-based enzyme-free immunoassay for rapid detection and subtyping of influenza A H1N1 and H3N2 viruses. Anal Chim Acta. 2015 Jul 9;883:37-44.

19. Wu SH, Chen KF, Chan YL. Severe hydrogen sulfide intoxication treated with therapeutic hypothermia. Am J Emerg Med. 2015 Sep;33(9):1327.e1-2.

20. Cheng CH, Chan PS, Hsieh YW, Chen KF. A meta-analysis of mismatch negativity in children with attention deficit-hyperactivity disorders. Neurosci Lett. 2016 Jan 26;612:132-7.

21. Hsu, CY; Liu, SH; Chao CH; Chan, YL; Tsai, TC; Chen, LM; Wu, CC; Chen, KF*. STROBE-compliant article: Blood Transfusions within the First 24 Hours of Hospitalization Did Not Impact Mortality Among Patients with Severe Sepsis. Medicine (Baltimore). 2016 Jan;95(4):e2601.

22. Tsou YK, Lee MS, Chen KF, Lin CH, Sung KF, Wu CC. Double-balloon enteroscopy-assisted endoscopic retrograde cholangiography for Roux-en-Y reconstruction patients with papilla of Vater or bilioenteric anastomosis. Scand J Gastroenterol. 2016 Jan;51(1):95-102.

23. Chen KF, Chaou CH, Jiang JY, Yu HW, Meng YH, Tang WC, Wu CC*. Diagnostic Accuracy of Lipopolysaccharide-Binding Protein as Biomarker for Sepsis in Adult Patients: A Systematic Review and Meta-Analysis. PLoS One. 2016 Apr 7;11(4):e0153188.

24. Li CJ*, Syue YJ, Lin YR, Cheng HH, Cheng FJ, Tsai TC, Chen KF*, Lee CH. Influence of CT utilisation on patient flow in the emergency department: a retrospective 1-year cohort study. BMJ Open. 2016 May 4;6(5):e010815.

25. Chen CK, Lin SC, Wu CC, Chen LM, Tzeng IS, Chen KF*. STARD-compliant article: The utility of red cell distribution width to predict mortality for septic patients visiting the emergency department. Medicine (Baltimore). 2016 Jun;95(24):e3692.

26. Liu SH, Chen KF, Chen CJ, Lin YH, Huang YC. Intermittent nasal carriage with Staphylococcus aureus within a menstrual cycle: Results from a prospective cohort of healthy carriers. Medicine (Baltimore). 2016 Jun;95(26):e4040.

27. Tzeng IS, Liu SH, Chen KF, Wu CC, Chen JC*. Impact of performance grading on annual numbers of acute myocardial infarction-associated emergency department visits in Taiwan: Results of segmented regression analysis. Medicine (Baltimore). 2016 Oct;95(42):e4937.

28. Chen KF, Liu SH, Li CH, Wu CC, Chaou CH, Tzeng IS, Hsieh YH, Blaney GN, Liu ZY, Han ST*, Chan YL*. Development and validation of a parsimonious and pragmatic CHARM score to predict mortality in patients with suspected sepsis. Am J Emerg Med. 2016 Oct; S0735-6757 (16):30801-4.

29. Chou HL, Han ST, Yeh CF, Tzeng IS, Hsieh TH, Wu CC, Kuan JT, Chen KF*. Systemic inflammatory response syndrome is more associated with bacteremia in elderly patients with suspected sepsis in emergency departments. Medicine (Baltimore). 2016 Dec;95(49):e5634.

30. Tzeng IS, Liu SH, Chiou YT, Huang CH, Lee CJ, Chien CY, Hsu SC, Weng YM, Chen KF*, Chen JC*. Predicting emergency departments visit rates from septicemia in Taiwan using an age-period-cohort model, 1998 to 2012. Medicine (Baltimore). 2016 Dec;95(50):e5598.

31. Chao HY, Liu PH, Lin SC, Chen CK, Chen JC, Chan YL, Wu CC, Blaney GN, Liu ZY, Wu CJ, Chen KF*. Association of in-hospital mortality and dysglycemia in septic patients. PLOS ONE. 2017 Jan 20;12(1):e0170408.

32. Chien CY, Chen YH, Han ST, Blaney GN., Huang TS, Chen KF*. The Number of Displaced Rib Fractures is More Predictive for Complications in Chest Trauma Patients. Scandinavian Journal of Trauma Resuscitation and Emergency Medicine. 2017 Feb 28;25(1):19.

33. Chiu CY, Chan YL, Tsai YS, Chen SA, Wang CJ, Chen KF, Chung IF. Airway Microbial Diversity is Inversely Associated with Mite-Sensitized Rhinitis and Asthma in Early Childhood. Sci Rep. 2017 May 12;7(1):1820.

34. Chien CH, Chen LW, Lin CL, Chang SW, Shyu YC, Chen KF, Chen SW, Hu CC, Yu CY, Chien RN. Unawareness of Hepatitis B Virus Infection confers on Higher Rate of Metabolic Syndrome: A Community-based Study. Sci Rep. 2017 Aug 29;7(1):9869.

35. Wu CC, Lan HM, Han ST, Chaou CH, Yeh CF, Liu SH, Li CH, Blaney GN 3rd, Liu ZY, Chen KF*. Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C-reactive protein: a systematic review and meta-analysis. Ann Intensive Care. 2017 Sep 6;7(1):91.

36. Chan YL, Han ST, Li CH, Wu CC, Chen KF*. Transfusion of Red Blood Cells to Patients with Sepsis. Int J Mol Sci. 2017 Sep 11;18(9).

37. Cheng CT, Yeh CN, Chiang KC, Yeh TS, Chen KF, Chen SW. Effects of cholecystectomy on recurrent biliary complications after endoscopic treatment of common bile duct stone: a population-based cohort study. Surg Endosc. 2017 Sep 15.
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