Chairman
1. Name and Photo
Chee-Jen Chang
2. Institution→Chang Gung University
3. Position→Director/Professor
4. Department→
Graduate Institute of Clinical Medical Science
Clinical Informatics and Medical Statistics Research Center
Research Services Center For Health Information
Resource Center for Clinical Research
5. Address→No.259, Wunhua 1st Rd., Gueishan District, Taoyuan City 33302, Taiwan (R.O.C.)
6. Tel(GSM optional)/Fax→+886-3-2118800#3577/ +886-3-2118453
7. E-mail： cjchang@mail.cgu.edu.tw
8. Personal Website→http://163.25.110.97/joomla/
9.Focus of Interest：
Clinical Trial Design.
Statistical modeling in pharmacoeconomics and outcome research.
Strategy and methodology approaches and statistical data analysis to clinical trials, clinical epidemiology research, and basic science experiments.
Strategical planning, study design and data analysis in pharmacoeconomics.
Statistical methodology development in bridging studies.
Data mining technique applied to the biomedical data sets.
Data analysis in microarray data and proteomics.
BI in clinical informatics.
Data analysis IT tool in clinical trials.
Methods for Health Technology Assessment.
10.Fulltime Employment：
PROFESSIONAL APPOINTMENT
Professor (2005 ~ current) Graduate Institute of Clinical Medical Science, Chang Gung University.
Jointly Appointed Professor (2018 ~ current) Department of Biomedical Sciences, Chang Gung University.
Director (2009 ~ current) Clinical Informatics and Medical Statistics Research Center, Chang Gung University.
Director (2013 ~ current) Research Services Center for Health Information, Chang Gung University.
Adjunct Professor (2005 ~ current) Graduate Institute of Clinical Medicine and Graduate Institute of Clinical Pharmacy, School of Medicine, National Taiwan University.
Adjunct Professor (2007 ~ current) Graduate Institute of Medical Mechatronics, Chang Gung University.
Executive Director (2018 ~ current) Taiwan Society for Pharmacoeconomics and Outcome Research (TaSPOR).
WORKING EXPERIENCE
President (2015 ~ 2017) Taiwan Society for Pharmacoeconomics and Outcome Research.
Member of Editorial advisory board (2015~2017), Value in Health Regional Issue for Asia Issues.
Co-Editor (2014 ~ 2016) News Across Asia, ISPOR Asia Consortium Newsletter.
Chair (2012 ~ 2014) Publication Committee, ISPOR Asia Consortium.
President (2013 ~ 2014) Taiwan Society for Pharmacoeconomics and Outcome Research.
Chair (2012 ~ 2017), Internation Society for Pharmacoeconomics and Outcome Research, Taiwan chapter.
Director (2005 ~ 2016) Statistical Center for Clinical Research, Chang Gung Memorial Hospital.
Professor (2005 ~ 2006) Graduate Institute of Basic Medical Science, Chang Gung University.
Director (2003 ~ 2005) Bioinformatics and Biostatistics Core, National Taiwan University Center for Genomic Medicine.
Deputy Director (2000 ~ 2005) Clinical Trial Center, Natioanl Taiwan Universiy Hospital.
Associate Research Fellow (2000 ~ 2005) Division of Clinical Medicine, National Taiwan University Hospital, School of Medicine, National Taiwan Univsersity.
Adjunct Associate Professor (2000 ~ 2005)Graduate Institute of Clinical Medicine and Graduate Institute of Clinical Pharmacy, National Taiwan University School of Medicine.
Biostatistical Core Director (1997 ~ 2000) General Clinical Research Center, Albert Einstein College of Medicine.
Director (1997 ~ 2000) Biostatistics Core, Comprehensive Cancer Center, Albert Einstein College of Medicine
Associate Professor (1997 ~ 2000) Division of Epidemiology and Biostatistics, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine.
Adjunct Senior Lecturer (1998 ~ 1999) Graduate School of Health Sciences, New York Medical College.
Director (1996 ~ 2000) Biostatistical Facility, Albert Einstein College of Medicine
Assistant Professor (1992 ~ 1997) Division of Epidemiology and Biostatistics, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine.
Instructor (1991 ~ 1992)Division of Epidemiology and Biostatistics, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine.
Senior Statistical Consultant (1989 ~ 1991) Statistical Consultant Center, University of Iowa.
Instructor (1988 ~ 1989) Department of Statistics and Actuarial Science, University of Iowa.
Research Assistant (1983 ~ 1988) Department of Statistics and Actuarial Science, University of Iowa.
System Analyst / Programmer (1979 ~ 1983) Department of Information System, Computer Center, The Bank of Taiwan. Taipei, Taiwan.
11.Education：
Ph.D. Department of Statistics, University of Iowa, Iowa City, Iowa. 1991.
M.S. Department of Mathematics, University of Iowa, Iowa City, Iowa. 1985.
B.S. Department of Applied Mathematics, National Chiao Tung University, Taiwan. 1979.
12.Honors and Awards：
(1)International Society for Pharmacoeconomics and Outcomes Research Asia Consortium, Chair-elect, Advisory Committee.(2017-2019)
(2)Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease（2018/02 JAMA: The Journal of the American Medical Association，2016 IF: 44.405, Rank: 3/155)
13.SelectedMain Publications（up to 5 ）：
(1) Gau-Tzu Chen, Shu-Chen Chang, Chee-Jen Chang* (2018, May). New Drug Reimbursement and Pricing Policy in Taiwan. Value in Health Regional Issues, 15, 127-132.
(2) Chee-Jen Chang, Tse-Chih Chou, Chiung-Chih Chang, Ta-Fu Chen, Chaur-Jong Hu, Jong-Ling Fuh, Wenfu Wang, Chiung-Mei Chen, Winco Hsu, Chin-Chang Huang* (2019). Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance research database of Taiwan. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 5, 46-51.
(3) Chia-Jui Yang, Hsiu-Yin Wang, Tse-Chih Chou, Chee-Jen Chang* (2019, Oct). Prevalence and related drug cost of comorbidities in HIV-infected patients receiving highly active antiretroviral therapy in Taiwan: A cross-sectional study. Journal of Microbiology, Immunology and Infection, 52(5), 720-727.
(4) Chia-Hsuan Tsai, Hsiang-Hao Hsu, Shih-Heng Chen, Ling Chien, Jennifer An-Jou Lin, Chee-Jen Chang*, Huang-Kai Kao*. (2020, Jan). Incidence and Risk of Carpal Tunnel Syndrome in End-Stage Renal Disease Patients on Dialysis: A Nationwide Population-Based Matched Cohort Study. Ann Plast Surg, 84(1S Suppl 1), S100-S106.
(5) Chih-Kuo Lee, Tzung-Dau Wang*, Hsiao-Ting Juang, Shu-Chen Chang, Heng-Yu Pan, Donna Shu-Han Lin, Chee-Jen Chang*. (2021, Jul). Efficacy and safety of ticagrelor versus clopidogrel in patients with non-ST-elevation myocardial infarction in Taiwan. Scientific Reports, 11, 14150.
14.Patents：|
2016/8/1~2035/1/4
METHOD FOR PREDICTING HEPATOCELLULAR CARCINOMA OCCURRENCE IN LIVER CIRRHOTIC PATIENTS
15.Board Certification：Taiwan Society for Pharmacoeconomics and Outcome Research
16.Ongoing projects：
(1) SCRPD1G0161 2017/4/21~2022/12/31 Real World Cancer Treatment Pattern and Distribution in Taiwan
(2) NMRPD1L0361 2021/8/1~2022/7/31
(3) SCRPD1M0061 2022/1/18~2022/4/30 Incidence, Mortality, Disease Burden of HPV (lMDB study) – Extension Project
17.All publications：
(1) Mahmoudi E*, Lu YW, Chang SC, Lin CY, Wang YC, Chang CJ*, Cheng MH, Chung KC. 2017,08. The Associations of Hospital Volume, Surgeon Volume, and Surgeon Experience with Complications and 30-day Rehospitalization after Free Tissue Transfer: A National Population Study. Plastic and Reconstructive Surgery. 140(2):403-411. (SCI)
(2) Cheng-Hsu Wang*, Chee-Jen Chang, Kun-Yun Yeh, Pei-Hung Chang, Jen-Seng Huang. 2017,08. The Prognostic Value of HER2-Positive Circulating Tumor Cells in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Clin Breast Cancer. 17(5):341-349. (SCI)
(3) Mahmoudi E*, Lu YW, Chang SC, Lin CY, Wang YC, Chang CJ, Cheng MH*, Chung KC. 2017,09. Associations of Surgeon and Hospital Volumes with Outcome for Free Tissue Transfer by Using the National Taiwan Population Healthcare Data from 2001-2012. Plastic and Reconstructive Surgery. 140(3):455e-465e. (SCI)
(4) Ying-Chang Tung, Yu-Chang Huang, Lung-Sheng, Chee-Jen Chang, Pao-Hsien Chu*. 2017,10. Medication compliance and clinical outcomes of fixed- dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment. J Clin Hypertens. 19(10):983-989. (SCI)
(5) Elham Mahmoudi*, Yiwen Lu, Shu-Chen Chang, Chia-Yu Lin, Yi-Chun Wang, Chee Jen Chang, Ming-Huei Cheng, Kevin C. Chung. 2017,10. Association of High-Volume Surgeons Working in High-Volume Hospitals with Cost of Free Flap Surgeries. Plast Reconstr Surg Glob Open. 5(10):e1520.
(6) Chung-Yen Lu, Hsin-Chia Huang, Hen-Hong Chang, Tsung-Hsien Yang, Chee-Jen Chang, Su-Wei Chang, Pei-Chun Chen*. 2017,11. Acupuncture therapy and incidence of depression after stroke. Stroke. 48(11):1682-1684. (SCI)
(7) Chang-Teng Wu, Chyi-Liang Chen, Hao-Yuan Lee*, Chee-Jen Chang, Pi-Yu Liu, Chin-Ying Li, Ming-Ying Liu, Chien-Hsisung Liu. 2017,12. Decreased antimicrobial resistance and defined daily doses after implementation of a clinical culture-guided antimicrobial stewardship program in a local hospital. Journal of Microbiology, Immunology and Infection. 50(6):846-856. (SCI)
(8) Shyue-Luen Chang, Yau-Li Huang, Mei-Ching Lee, Sindy Hu, Yen-Chang Hsiao, Su-Wei Chang, Chee Jen Chang, Pei-Chun Chen*. 2018,02. Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease. JAMA. 319(8):807-817. (SCI)
(9) Chuang-Wei Wang, Lan-Yan Yang, Chun-Bing Chen, Hsin-Chun Ho, Shuen-Iu Hung, Chih-Hsun Yang, Chee-Jen Chang, Shih-Chi Su, Rosaline Chung-Yee Hui, See-Wen Chin, Li-Fang Huang, Yang Yu-Wei Lin, Wei-Yang Chang, Wen-Lang Fan, Chin-Yi Yang, Ji-Chen Ho, Ya-Ching Chang, Chun-Wei Lu, Wen-Hung Chung*, the Taiwan Severe Cutaneous Adverse Reaction (TSCAR) Consortium. 2018,05. Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions. J Clin Invest.. 128(3):985-996. (SCI)
(10) Yi-Ming Weng, Chip-Jin Ng, Chen-June Seak, Cheng-Yu Chien, Kuan-Fu Chen, Jr-Rung Lin, Chee-Jen Chang*. 2018,05. One-year survival rate and healthcare costs after cardiac arrest in Taiwan, 2006–2012. PLOS ONE. 13(5):e0196687. (SCI)
(11) Gau-Tzu Chen, Shu-Chen Chang, Chee-Jen Chang*. 2018,05. New Drug Reimbursement and Pricing Policy in Taiwan. Value in Health Regional Issues. 15:127-132.
(12) Laura Liu, Ijilmurun Enkh-Amgalan, Nan-Kai Wang, Lan-Hsin Chuang, Yen-Po Chen, Yih-shiou Hwang, Chee-Jen Chang, Kuan-Jen Chen, Wei-chi Wu, Tun-Lu Chen, Chi-Chun Lai*. 2018,05. RESULTS OF MACULAR HOLE SURGERY: Evaluation Based on the International Vitreomacular Traction Study Classification. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES. 38(5):900-906. (SCI)
(13) Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Jung-Ju Huang, Zung-Chung Chen, Chee-Jen Chang, Lun-Jou Lo, Philip Kuo-Ting Chen*, Jyh-Ping Chen, Yu-Ray Chen. 2018,05. Clinical evaluation of silicone gel in the treatment of cleft lip scars. Scientific Reports. 8(1):7422. (SCI)
(14) Shing-Hsien Chou, Ying-Chang Tung, Lung-Sheng Wu, Chee-Jen Chang, Suefang Kung*, Pao-Hsien Chu*. 2018,07. Severity of chronic periodontitis and risk of gastrointestinal cancers: A population-based follow-up study from Taiwan. Medicine. 97(27):e11386. (SCI)
(15) Chih-Chen Chang, Shih-Hsiang Chen, Tsung-Yen Chang, Chao-Jan Wang, Wendy Yang, Chee-Jen Chang, Tang-Her Jaing*. 2018,07. Relationship between the Computed Tomography - Measured Initial Primary Tumor Volume, Urine VMA Level and Stage in Neuroblastoma Patients. Iran J Radiol. 15(3):e63270. (SCI)
(16) Chen-Yu Li, Chee-Jen Chang, Wen-Jung Chung, Cheng-Jui Lin, Shu-Kai Hsueh, Chien-Ho Lee, Chiung-Jen Wu, Tzu-Hsien Tsai, Cheng-I Cheng*. 2018,07. Assessment of CHA2DS2-VASc score for predicting cardiovascular and cerebrovascular outcomes in acute myocardial infarction patients. Medicine. 97(28):e11230. (SCI)
(17) Chee-Jen Chang, Tse-Chih Chou, Chiung-Chih Chang, Ta-Fu Chen, Chaur-Jong Hu, Jong-Ling Fuh, Wenfu Wang, Chiung-Mei Chen, Winco Hsu, Chin-Chang Huang*. 2018,07. Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance research database of Taiwan. Alzheimer's & Dementia: Translational Research & Clinical Interventions. 5:46-51.
(18) Feng-Chih Kuo*, Chee-Jen Chang*, Kerri L. Bell, Mel S. Lee, Jun-Wen Wang. 2018,10. No Difference in Morbidity and Mortality After Total Joint Arthroplasty in Liver Transplant Recipients: A Propensity Score-Matched Analysis of a Nationwide, Population-Based Study Using Universal Healthcare Data. The Journal of Arthroplasty. 33(10):3147-3152. (SCI)
(19) Yi‑Hsuan Lin, Yu‑Yao Huang, Yi‑Ling Wu, Cheng‑Wei Lin, Pei‑Chun Chen, Chee Jen Chang, Sheng‑Hwu Hsieh, Jui‑Hung Sun, Szu‑Tah Chen, Chia‑Hung Lin*. 2018,10. Coadministration of DPP-4 inhibitor and insulin therapy does not further reduce the risk of cardiovascular events compared with DPP-4 inhibitor therapy in diabetic foot patients: a nationwide population-based study. Diabetology & Metabolic Syndrome. 10:75. (SCI)
(20) Chern-Horng Lee, Chee-Jen Chang, Yu-Jr Lin, Cho-Li Yen, Chien-Heng Shen, Ya-Ting Cheng, Chen-Chun Lin, Sen-Yung Hsieh*. 2018,11. Nomogram predicting extrahepatic metastasis of hepatocellular carcinoma based on commonly available clinical data. JGH Open. 3(1):38-45.
(21) Chien-Te Ho, Ying‐Chang Tung, Shing‐Hsien Chou, Fu‐Chih Hsiao, Yu‐Sheng Lin, Chee‐Jen Chang, Pao‐Hsien Chu*, FCCP, FACC, FESC, FAPSC. 2018,12. Clinical outcomes in hypertensive patients treated with a single‐pill fixed‐dose combination of renin‐angiotensin system inhibitor and thiazide diuretic. J Clin Hypertens. 20(12):1731-1738. (SCI)
(22) Yu-Chih Lin*, Shen-Hsun Lee, I-Jung Chen, Chih-Hsiang Chang*, Chee-Jen Chang*, Yi-Chun Wang, Yuhan Chang, Pang-Hsin Hsieh*. 2018,12. Symptomatic pulmonary embolism following hip fracture: A nationwide study. Thrombosis Research. 172:120-127. (SCI)
(23) Yu-Chih Lin, Chih-Hsiang Chang, Chee-Jen Chang, Yi-Chun Wang, Pang-Hsin Hsieh, Yuhan Chang*. 2019,01. Vascular injury during primary total knee arthroplasty: A nationwide study. Journal of the Formosan Medical Association. 118:305-310. (SCI)
(24) Chyong-Huey Lai*, Elizabeth Vallikad, Hao Lin, Lan-Yan Yang, Shih-Ming Jung, Hsueh-Erh Liu, Yu-Che Ou, Hung-Hsueh Chou, Cheng-Tao Lin, Huei-Jean Huang, Kuan-Gen Huang, Jiantai Qiu, Yao-Ching Hung, Tzu-I Wu, Wei-Yang Chang, Kien-Thiam Tan, Chiao-Yun Lin, Angel Chao, Chee-Jen Chang. 2019,01. Maintenance of pegylated liposomal doxorubicin/carboplatin in patients with advanced ovarian cancer: randomized study of an Asian Gynecologic Oncology Group. Journal of Gynecologic Oncology. 31(1):e5. (SCI)
(25) Shih‐Chi Su, Chun‐Bing Chen, Wan‐Chun Chang, Chuang‐Wei Wang, Wen‐Lang Fan, Lai‐Ying Lu, Ryosuke Nakamura, Yoshiro Saito, Mayumi Ueta, Shigeru Kinoshita, Chonlaphat Sukasem, Kittika Yampayon, Pornpimol Kijsanayotin, Nontaya Nakkam, Niwat Saksit, Wichittra Tassaneeyakul, Michiko Aihara, Yu‐Jr Lin, Chee‐Jen Chang, Tony Wu, Shuen‐Iu Hung*, Wen‐Hung Chung*. 2019,02. HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians. Clinical Pharmacology and Therapeutics. 105(2):476-485. (SCI)
(26) Chun-Li Wang, Pei-Chun Chen, Hsiao-Ting Juang, Chee-Jen Chang*. 2019,04. Adverse Outcomes Associated with Pre-Existing and New-Onset Atrial Fibrillation in Patients with Acute Coronary Syndrome: A Retrospective Cohort Study. Cardiol Ther. 8(1):117-127.
(27) Hung-Yu Huang, Chun-Yu Lo, Lan-Yan Yang, Fu-Tsai Chung, Te-Fang Sheng, Horng-Chyuan Lin, Chang-Wei Lin, Yu-Chen Huang, Chee-Jen Chang, Kian Fan Chung, Chun-Hua Wang*. 2019,04. Maintenance Negative Pressure Ventilation Improves Survival in COPD Patients with Exercise Desaturation. J Clin Med. 8(4):562. (SCI)
(28) Alena Strizek*, Chee-Jen Chang, Wesley Furnback, Bruce Wang, Jérémie Lebrec, Thomas Lew. 2019,05. The Cost of Hypoglycemia Associated With Type 2 Diabetes Mellitus in Taiwan. Value in Health Regional Issues. 18:84-90.
(29) Chi-Hua Chen, Chun-Bing Chen, Chee Jen Chang, Yu Jr Lin, Chuang-Wei Wang, Ching-Chi Chi, Chun-Wei Lu, Wei-Ti Chen, Ren-You Pan, Shih-Chi Su, Lung-An Hsu, Ya-Ching Chang, Kuang-Hui Yu, Yeong-Jian Jan Wu, Ko-Ming Lin, Shuen-Iu Hung, Shin-Ming Chen*, Wen-Hung Chung*. 2019,08. Hypersensitivity and Cardiovascular Risks Related to Allopurinol and Febuxostat Therapy in Asians: A Population-Based Cohort Study and Meta-Analysis. Clinical Pharmacology and Therapeutics. 106(2):391-401. (SCI)
(30) Chia-Jui Yang, Hsiu-Yin Wang, Tse-Chih Chou, Chee-Jen Chang*. Prevalence and related drug cost of comorbidities in HIV-infected patients receiving highly active antiretroviral therapy in Taiwan: A cross-sectional study. 2019,10. Journal of Microbiology, Immunology and Infection. 52(5):720-727. (SCI)
(31) Dong-Yi Chen, Chen-Yu Li, Ming-Jer Hsieh, Chun-Chi Chen, I-Chang Hsieh, Tien-Hsing Chen, Shao-Wei Chen, Chao-Yung Wang, Shang-Hung Chang, Cheng-Hung Lee, Ming-Lung Tsai, Ming-Yun Ho, Jih-Kai Yeh, Chee-Jen Chang*, Ming-Shien Wen*. 2019,10. Predictors of subsequent myocardial infarction, stroke, and death in stable post-myocardial infarction patients: A nationwide cohort study. European Heart Journal: Acute Cardiovascular Care. 8(7):634-642
(32) Chia-Hsuan Tsai, Hsiang-Hao Hsu, Shih-Heng Chen, Ling Chien, Jennifer An-Jou Lin, Chee-Jen Chang*, Huang-Kai Kao*. 2020,01. Incidence and Risk of Carpal Tunnel Syndrome in End-Stage Renal Disease Patients on Dialysis: A Nationwide Population-Based Matched Cohort Study. Ann Plast Surg. 84(1S Suppl 1):S100-S106. (SCI)
(33) Hung-Yu Huang, Shih-Wei Lin, Li-Pang Chuang, Chih-Liang Wang, Ming-Hui Sun, Hsueh-Yu Li, Chee-Jen Chang, Shu-Chen Chang, Cheng-Ta Yang, Ning-Hung Chen*. 2020,07. Severe Obstructive Sleep Apnea Associated With Higher Risk of Mortality in Stage III and IV Lung Cancer. Journal of Clinical Sleep Medicin. 16(7):1091-1098. (SCI)
(34) Chun-Bing Chen, Tsun-Hao Hsu, Rosaline Chung-Yee Hui, Chun-Wei Lu, Wei-Ti Chen, Pin-Hsuan Chiang, Chuang-Wei Wang, Shiow-Shuh Chuang, Jui-Yung Yang, Shih-Yi Yang, Shu-Ying Chang, Yen-Chang Hsiao, Kuo-Chin Kao, Han-Chung Hu, Ting-Shu Wu, Chao-Wei Hsu, David Hui-Kang Ma, Shin-Yi Chen, Ya-Chung Tian, Chi-Yuan Cheng, Chi-Hua Chen, Min-Hui Chi, Ming-Ying Wu, Ren-Feng Liu, Chi-Hui Wang, Ya-Ching Chang, Jing-Yi Lin, Hsin-Chun Ho, Yang Yu-Wei Lin, Chee Jen Chang, Yu-Jr Lin, Cheng-Lung Ku, Shuen-Iu Hung, Wen-Hung Chung*, Taiwan Severe Cutaneous Adverse Reaction Consortium. 2020,08. Disseminated intravascular coagulation in Stevens-Johnson syndrome and toxic epidermal necrolysis. J Am Acad Dermatol. 84(6):1782-1791. (SCI)
(35) Hsien-Yi Chiu, Chee Jen Chang, Yu Jr Lin, Tsen-Fang Tsai*. 2020,09. National trends in incidence, mortality, hospitalizations, and expenditures for pemphigus in Taiwan. Journal of Dermatological Science. 99(3):203-208. (SCI)
(36) Tzu-Yu Lin, Chi-Yuan Cheng, Yi-Chia Chen, Shu-Chen Chang, Chi-Hua Chen*, Chee-Jen Chang. 2020,10. The cancer-specific survival benefit of adjuvant chemotherapy for patients aged 75 or older with stage III colon cancer. Formosa Journal of Clinical Pharmacy. 28(4):320-334.
(37) Chih-Hsiang Chang, Sheng-Hsun Lee, Yu-Chih Lin, Yi-Chun Wang, Chee-Jen Chang, Pang-Hsin Hsieh*. 2020,11. Increased periprosthetic hip and knee infection projected from 2014 to 2035 in Taiwan. Journal of Infection and Public Health. 13(11):1768-1773. (SCI)
(38) Chih-Hsiang Chang, Chee-Jen Chang, Yi-Chun Wang, Chih-Chien Hu, Yuhan Chang, Pang-Hsin Hsieh, Dave W Chen*. 2020,9-12. Increased incidence, morbidity, and mortality in cirrhotic patients with hip fractures: A nationwide population-based study. J Orthop Surg (Hong Kong). 28(3):2309499020918032. (SCI)
(39) Shih-Chiang Huang, Kwai-Fong Ng, Ian Yi-Feng Chang, Chee-Jen Chang, Yi-Chun Chao, Shu-Chen Chang, Min-Chi Chen, Ta-Sen Yeh, Tse-Ching Chen*. 2021,01. The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes. PLOS ONE. 16(1):e0245356. (SCI)
(40) Chun-Bing Chen, Kang-Ling Kuo, Chuang-Wei Wang, Chun-Wei Lu, Rosaline Chung-Yee Hui, Kun-Lin Lu, Wan-Chun Chang, Wei-Ti Chen, Fu Yun, Yu-Chuan Teng, Hua-En Lee, Jing-Yi Lin, Hsin-Chun Ho, Min-Hui Chi, Yang Yu-Wei Lin, Chee Jen Chang, Yu Lin Jr, Cheng-Lung Ku, Shuen-Iu Hung, Ya-Ching Chang, Wen-Hung Chung*, Taiwan Severe Cutaneous Adverse Reaction Consortium. 2021,03. Detecting Lesional Granulysin Levels for Rapid Diagnosis of Cytotoxic T lymphocyte-Mediated Bullous Skin Disorders. J Allergy Clin Immunol Pract. 9(3):1327-1337.e3. (SCI)
(41) Shyue-Luen Chang, Sindy Hu, Yau-Li Huang, Mei-Ching Lee, Wen-Hung Chung, Chun-Yu Cheng, Yen-Chang Hsiao, Chee Jen Chang, Shu Ru Lee, Su-Wei Chang, Yu-Wen Wen*. 2021,03. Treatment of Varicose Veins Affects the Incidences of Venous Thromboembolism and Peripheral Artery Disease. Circ Cardiovasc Interv. 14(3):e010207. (SCI)
(42) Chen CB, Chen YE, Chu MT, Wang CW, Hui RC, Lu CW, Hsiao YP, Chu CY, Chang MM, Cheung CM, Cheng CY, Wang YW, Lin YJ, Chang CJ, Hung SI*, Chung WH*, Taiwan Severe Cutaneous Adverse Reaction Consortium. 2021,03. The risk of anti-osteoporotic agent-induced severe cutaneous adverse drug reactions and their association with HLA. J Eur Acad Dermatol Venereol. 35(3):712-720. (SCI)
(43) Li-Chung Chiu, Li-Pang Chuang, Shaw-Woei Leu, Yu-Jr Lin, Chee-Jen Chang, Hsin-Hsien Li, Feng-Chun Tsai, Chih-Hao Chang, Chen-Yiu Hung, Shih-Wei Lin, Han-Chung Hu, Chung-Chi Huang, Huang-Pin Wu, Kuo-Chin Kao*. 2021,03. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome: Propensity Score Matching. Membranes. 11(6):393. (SCI)
(44) Chuang-Wei Wang, Wichittra Tassaneeyakul, Chun-Bing Chen, Wei-Ti Chen, Yu-Chuan Teng, Cheng-Yang Huang, Chonlaphat Sukasem, Chun-Wei Lu, Yun-Shien Lee, Siew-Eng Choon, Nontaya Nakkam, Rosaline Chung-Yee Hui, Yen-Hua Huang, Ya-Ching Chang, Yang Yu-Wei Lin, Chee-Jen Chang, Tsu-Man Chiu, Wasun Chantratita, Parinya Konyoung, Chaw-Ning Lee, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Warayuwadee Amornpinyo, Niwat Saksit, Pawinee Rerknimitr, Huang Yu Huei, Shang-Hong Lin, Chao-Kai Hsu, Wen-Lang Fan, Cheng-Chi Chan, Yu-Jr Lin, Shuen-Iu Hung*, Wen-Hung Chung*, Taiwan/Asian Severe Cutaneous Adverse Reaction Consortium. 2021,04. Whole Genome Sequencing Identifies Genetic Variants Associated with Co-trimoxazole Hypersensitivity in Asians. Journal of Allergy and Clinical Immunology. 147(4):1402-1412. (SCI)
(45) Jui-Fan Chiang, Ming-Hui Sun*, Kuan-Jen Chen, Wei-Chi Wu, Chi-Chun Lai, Chee-Jen Chang, Yu-Jr Lin, Shu-Chen Chang, Hung-Yu Huang, Ning-Hung Chen, Hsueh-Yu Li. 2021,06. Association between obstructive sleep apnea and diabetic macular edema in patients with type 2 diabetes. Am J Ophthalmol. 226:217-225. (SCI)
(46) Chih-Kuo Lee, Tzung-Dau Wang*, Hsiao-Ting Juang, Shu-Chen Chang, Heng-Yu Pan, Donna Shu-Han Lin, Chee-Jen Chang*. 2021,07. Efficacy and safety of ticagrelor versus clopidogrel in patients with non-ST-elevation myocardial infarction in Taiwan. Scientific Reports. 11:14150. (SCI)
(47) Hung-Yu Huang, Chee-Jen Chang, Shu-Chen Chang, Li-Fu Li*. 2021,08. Author Reply to letter to the editor "clinical outcomes and prognostic factors for prolonged mechanical ventilation in patients with acute stroke and brain trauma". J Formos Med Assoc. 120(8):1658-1659. (SCI)
(48) Sheng-Hsun Lee,Yu-Chih Lin, Chee-Jen Chang, Chih-Yun Fan Chiang, Szu-Yuan Chen, Yu-Han Chang, Pang-Hsin Hsieh, Chih-Hsiang Chang*. 2021,10. Outcome and Cost Analysis of Primary Total Knee Arthroplasty in End-stage Renal Disease Patients: A Nationwide Population-based Study. Biomed J. 44(5):620-626. (SCI)
(49) Hung-Yu Huang, Chung-Shu Lee, Tzu-Hsuan Chiu, Hsiang Hsuan Chen, Li-Yi Chan, Chee-Jen Chang, Shu-Chen Chang, Han-Chung Hu, Kuo-Chin Kao, Ning-Hung Chen, Shu-Min Lin, Li-Fu Li*. 2022,01. Clinical outcomes and prognostic factors for prolonged mechanical ventilation in patients with acute stroke and brain trauma. J. Formos. Med. Assoc. 121(1 Pt 1):162-169. (SCI)
18.monograph & Book Papers
(1) Kenneth K. C. Lee, Wai Yee Choon, Chee Jen Chang, Jeff Guo and Paul Scuffham. (2022). Increasing Importance of Patients-generated Real World Data for Healthcare Policy Decisions about Medicinal Products. Frontiers in Pharmacology.
Chee-Jen Chang
2. Institution→Chang Gung University
3. Position→Director/Professor
4. Department→
Graduate Institute of Clinical Medical Science
Clinical Informatics and Medical Statistics Research Center
Research Services Center For Health Information
Resource Center for Clinical Research
5. Address→No.259, Wunhua 1st Rd., Gueishan District, Taoyuan City 33302, Taiwan (R.O.C.)
6. Tel(GSM optional)/Fax→+886-3-2118800#3577/ +886-3-2118453
7. E-mail： cjchang@mail.cgu.edu.tw
8. Personal Website→http://163.25.110.97/joomla/
9.Focus of Interest：
Clinical Trial Design.
Statistical modeling in pharmacoeconomics and outcome research.
Strategy and methodology approaches and statistical data analysis to clinical trials, clinical epidemiology research, and basic science experiments.
Strategical planning, study design and data analysis in pharmacoeconomics.
Statistical methodology development in bridging studies.
Data mining technique applied to the biomedical data sets.
Data analysis in microarray data and proteomics.
BI in clinical informatics.
Data analysis IT tool in clinical trials.
Methods for Health Technology Assessment.
10.Fulltime Employment：
PROFESSIONAL APPOINTMENT
Professor (2005 ~ current) Graduate Institute of Clinical Medical Science, Chang Gung University.
Jointly Appointed Professor (2018 ~ current) Department of Biomedical Sciences, Chang Gung University.
Director (2009 ~ current) Clinical Informatics and Medical Statistics Research Center, Chang Gung University.
Director (2013 ~ current) Research Services Center for Health Information, Chang Gung University.
Adjunct Professor (2005 ~ current) Graduate Institute of Clinical Medicine and Graduate Institute of Clinical Pharmacy, School of Medicine, National Taiwan University.
Adjunct Professor (2007 ~ current) Graduate Institute of Medical Mechatronics, Chang Gung University.
Executive Director (2018 ~ current) Taiwan Society for Pharmacoeconomics and Outcome Research (TaSPOR).
WORKING EXPERIENCE
President (2015 ~ 2017) Taiwan Society for Pharmacoeconomics and Outcome Research.
Member of Editorial advisory board (2015~2017), Value in Health Regional Issue for Asia Issues.
Co-Editor (2014 ~ 2016) News Across Asia, ISPOR Asia Consortium Newsletter.
Chair (2012 ~ 2014) Publication Committee, ISPOR Asia Consortium.
President (2013 ~ 2014) Taiwan Society for Pharmacoeconomics and Outcome Research.
Chair (2012 ~ 2017), Internation Society for Pharmacoeconomics and Outcome Research, Taiwan chapter.
Director (2005 ~ 2016) Statistical Center for Clinical Research, Chang Gung Memorial Hospital.
Professor (2005 ~ 2006) Graduate Institute of Basic Medical Science, Chang Gung University.
Director (2003 ~ 2005) Bioinformatics and Biostatistics Core, National Taiwan University Center for Genomic Medicine.
Deputy Director (2000 ~ 2005) Clinical Trial Center, Natioanl Taiwan Universiy Hospital.
Associate Research Fellow (2000 ~ 2005) Division of Clinical Medicine, National Taiwan University Hospital, School of Medicine, National Taiwan Univsersity.
Adjunct Associate Professor (2000 ~ 2005)Graduate Institute of Clinical Medicine and Graduate Institute of Clinical Pharmacy, National Taiwan University School of Medicine.
Biostatistical Core Director (1997 ~ 2000) General Clinical Research Center, Albert Einstein College of Medicine.
Director (1997 ~ 2000) Biostatistics Core, Comprehensive Cancer Center, Albert Einstein College of Medicine
Associate Professor (1997 ~ 2000) Division of Epidemiology and Biostatistics, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine.
Adjunct Senior Lecturer (1998 ~ 1999) Graduate School of Health Sciences, New York Medical College.
Director (1996 ~ 2000) Biostatistical Facility, Albert Einstein College of Medicine
Assistant Professor (1992 ~ 1997) Division of Epidemiology and Biostatistics, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine.
Instructor (1991 ~ 1992)Division of Epidemiology and Biostatistics, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine.
Senior Statistical Consultant (1989 ~ 1991) Statistical Consultant Center, University of Iowa.
Instructor (1988 ~ 1989) Department of Statistics and Actuarial Science, University of Iowa.
Research Assistant (1983 ~ 1988) Department of Statistics and Actuarial Science, University of Iowa.
System Analyst / Programmer (1979 ~ 1983) Department of Information System, Computer Center, The Bank of Taiwan. Taipei, Taiwan.
11.Education：
Ph.D. Department of Statistics, University of Iowa, Iowa City, Iowa. 1991.
M.S. Department of Mathematics, University of Iowa, Iowa City, Iowa. 1985.
B.S. Department of Applied Mathematics, National Chiao Tung University, Taiwan. 1979.
12.Honors and Awards：
(1)International Society for Pharmacoeconomics and Outcomes Research Asia Consortium, Chair-elect, Advisory Committee.(2017-2019)
(2)Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease（2018/02 JAMA: The Journal of the American Medical Association，2016 IF: 44.405, Rank: 3/155)
13.SelectedMain Publications（up to 5 ）：
(1) Gau-Tzu Chen, Shu-Chen Chang, Chee-Jen Chang* (2018, May). New Drug Reimbursement and Pricing Policy in Taiwan. Value in Health Regional Issues, 15, 127-132.
(2) Chee-Jen Chang, Tse-Chih Chou, Chiung-Chih Chang, Ta-Fu Chen, Chaur-Jong Hu, Jong-Ling Fuh, Wenfu Wang, Chiung-Mei Chen, Winco Hsu, Chin-Chang Huang* (2019). Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance research database of Taiwan. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 5, 46-51.
(3) Chia-Jui Yang, Hsiu-Yin Wang, Tse-Chih Chou, Chee-Jen Chang* (2019, Oct). Prevalence and related drug cost of comorbidities in HIV-infected patients receiving highly active antiretroviral therapy in Taiwan: A cross-sectional study. Journal of Microbiology, Immunology and Infection, 52(5), 720-727.
(4) Chia-Hsuan Tsai, Hsiang-Hao Hsu, Shih-Heng Chen, Ling Chien, Jennifer An-Jou Lin, Chee-Jen Chang*, Huang-Kai Kao*. (2020, Jan). Incidence and Risk of Carpal Tunnel Syndrome in End-Stage Renal Disease Patients on Dialysis: A Nationwide Population-Based Matched Cohort Study. Ann Plast Surg, 84(1S Suppl 1), S100-S106.
(5) Chih-Kuo Lee, Tzung-Dau Wang*, Hsiao-Ting Juang, Shu-Chen Chang, Heng-Yu Pan, Donna Shu-Han Lin, Chee-Jen Chang*. (2021, Jul). Efficacy and safety of ticagrelor versus clopidogrel in patients with non-ST-elevation myocardial infarction in Taiwan. Scientific Reports, 11, 14150.
14.Patents：|
2016/8/1~2035/1/4
METHOD FOR PREDICTING HEPATOCELLULAR CARCINOMA OCCURRENCE IN LIVER CIRRHOTIC PATIENTS
15.Board Certification：Taiwan Society for Pharmacoeconomics and Outcome Research
16.Ongoing projects：
(1) SCRPD1G0161 2017/4/21~2022/12/31 Real World Cancer Treatment Pattern and Distribution in Taiwan
(2) NMRPD1L0361 2021/8/1~2022/7/31
(3) SCRPD1M0061 2022/1/18~2022/4/30 Incidence, Mortality, Disease Burden of HPV (lMDB study) – Extension Project
17.All publications：
(1) Mahmoudi E*, Lu YW, Chang SC, Lin CY, Wang YC, Chang CJ*, Cheng MH, Chung KC. 2017,08. The Associations of Hospital Volume, Surgeon Volume, and Surgeon Experience with Complications and 30-day Rehospitalization after Free Tissue Transfer: A National Population Study. Plastic and Reconstructive Surgery. 140(2):403-411. (SCI)
(2) Cheng-Hsu Wang*, Chee-Jen Chang, Kun-Yun Yeh, Pei-Hung Chang, Jen-Seng Huang. 2017,08. The Prognostic Value of HER2-Positive Circulating Tumor Cells in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Clin Breast Cancer. 17(5):341-349. (SCI)
(3) Mahmoudi E*, Lu YW, Chang SC, Lin CY, Wang YC, Chang CJ, Cheng MH*, Chung KC. 2017,09. Associations of Surgeon and Hospital Volumes with Outcome for Free Tissue Transfer by Using the National Taiwan Population Healthcare Data from 2001-2012. Plastic and Reconstructive Surgery. 140(3):455e-465e. (SCI)
(4) Ying-Chang Tung, Yu-Chang Huang, Lung-Sheng, Chee-Jen Chang, Pao-Hsien Chu*. 2017,10. Medication compliance and clinical outcomes of fixed- dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment. J Clin Hypertens. 19(10):983-989. (SCI)
(5) Elham Mahmoudi*, Yiwen Lu, Shu-Chen Chang, Chia-Yu Lin, Yi-Chun Wang, Chee Jen Chang, Ming-Huei Cheng, Kevin C. Chung. 2017,10. Association of High-Volume Surgeons Working in High-Volume Hospitals with Cost of Free Flap Surgeries. Plast Reconstr Surg Glob Open. 5(10):e1520.
(6) Chung-Yen Lu, Hsin-Chia Huang, Hen-Hong Chang, Tsung-Hsien Yang, Chee-Jen Chang, Su-Wei Chang, Pei-Chun Chen*. 2017,11. Acupuncture therapy and incidence of depression after stroke. Stroke. 48(11):1682-1684. (SCI)
(7) Chang-Teng Wu, Chyi-Liang Chen, Hao-Yuan Lee*, Chee-Jen Chang, Pi-Yu Liu, Chin-Ying Li, Ming-Ying Liu, Chien-Hsisung Liu. 2017,12. Decreased antimicrobial resistance and defined daily doses after implementation of a clinical culture-guided antimicrobial stewardship program in a local hospital. Journal of Microbiology, Immunology and Infection. 50(6):846-856. (SCI)
(8) Shyue-Luen Chang, Yau-Li Huang, Mei-Ching Lee, Sindy Hu, Yen-Chang Hsiao, Su-Wei Chang, Chee Jen Chang, Pei-Chun Chen*. 2018,02. Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease. JAMA. 319(8):807-817. (SCI)
(9) Chuang-Wei Wang, Lan-Yan Yang, Chun-Bing Chen, Hsin-Chun Ho, Shuen-Iu Hung, Chih-Hsun Yang, Chee-Jen Chang, Shih-Chi Su, Rosaline Chung-Yee Hui, See-Wen Chin, Li-Fang Huang, Yang Yu-Wei Lin, Wei-Yang Chang, Wen-Lang Fan, Chin-Yi Yang, Ji-Chen Ho, Ya-Ching Chang, Chun-Wei Lu, Wen-Hung Chung*, the Taiwan Severe Cutaneous Adverse Reaction (TSCAR) Consortium. 2018,05. Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions. J Clin Invest.. 128(3):985-996. (SCI)
(10) Yi-Ming Weng, Chip-Jin Ng, Chen-June Seak, Cheng-Yu Chien, Kuan-Fu Chen, Jr-Rung Lin, Chee-Jen Chang*. 2018,05. One-year survival rate and healthcare costs after cardiac arrest in Taiwan, 2006–2012. PLOS ONE. 13(5):e0196687. (SCI)
(11) Gau-Tzu Chen, Shu-Chen Chang, Chee-Jen Chang*. 2018,05. New Drug Reimbursement and Pricing Policy in Taiwan. Value in Health Regional Issues. 15:127-132.
(12) Laura Liu, Ijilmurun Enkh-Amgalan, Nan-Kai Wang, Lan-Hsin Chuang, Yen-Po Chen, Yih-shiou Hwang, Chee-Jen Chang, Kuan-Jen Chen, Wei-chi Wu, Tun-Lu Chen, Chi-Chun Lai*. 2018,05. RESULTS OF MACULAR HOLE SURGERY: Evaluation Based on the International Vitreomacular Traction Study Classification. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES. 38(5):900-906. (SCI)
(13) Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Jung-Ju Huang, Zung-Chung Chen, Chee-Jen Chang, Lun-Jou Lo, Philip Kuo-Ting Chen*, Jyh-Ping Chen, Yu-Ray Chen. 2018,05. Clinical evaluation of silicone gel in the treatment of cleft lip scars. Scientific Reports. 8(1):7422. (SCI)
(14) Shing-Hsien Chou, Ying-Chang Tung, Lung-Sheng Wu, Chee-Jen Chang, Suefang Kung*, Pao-Hsien Chu*. 2018,07. Severity of chronic periodontitis and risk of gastrointestinal cancers: A population-based follow-up study from Taiwan. Medicine. 97(27):e11386. (SCI)
(15) Chih-Chen Chang, Shih-Hsiang Chen, Tsung-Yen Chang, Chao-Jan Wang, Wendy Yang, Chee-Jen Chang, Tang-Her Jaing*. 2018,07. Relationship between the Computed Tomography - Measured Initial Primary Tumor Volume, Urine VMA Level and Stage in Neuroblastoma Patients. Iran J Radiol. 15(3):e63270. (SCI)
(16) Chen-Yu Li, Chee-Jen Chang, Wen-Jung Chung, Cheng-Jui Lin, Shu-Kai Hsueh, Chien-Ho Lee, Chiung-Jen Wu, Tzu-Hsien Tsai, Cheng-I Cheng*. 2018,07. Assessment of CHA2DS2-VASc score for predicting cardiovascular and cerebrovascular outcomes in acute myocardial infarction patients. Medicine. 97(28):e11230. (SCI)
(17) Chee-Jen Chang, Tse-Chih Chou, Chiung-Chih Chang, Ta-Fu Chen, Chaur-Jong Hu, Jong-Ling Fuh, Wenfu Wang, Chiung-Mei Chen, Winco Hsu, Chin-Chang Huang*. 2018,07. Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance research database of Taiwan. Alzheimer's & Dementia: Translational Research & Clinical Interventions. 5:46-51.
(18) Feng-Chih Kuo*, Chee-Jen Chang*, Kerri L. Bell, Mel S. Lee, Jun-Wen Wang. 2018,10. No Difference in Morbidity and Mortality After Total Joint Arthroplasty in Liver Transplant Recipients: A Propensity Score-Matched Analysis of a Nationwide, Population-Based Study Using Universal Healthcare Data. The Journal of Arthroplasty. 33(10):3147-3152. (SCI)
(19) Yi‑Hsuan Lin, Yu‑Yao Huang, Yi‑Ling Wu, Cheng‑Wei Lin, Pei‑Chun Chen, Chee Jen Chang, Sheng‑Hwu Hsieh, Jui‑Hung Sun, Szu‑Tah Chen, Chia‑Hung Lin*. 2018,10. Coadministration of DPP-4 inhibitor and insulin therapy does not further reduce the risk of cardiovascular events compared with DPP-4 inhibitor therapy in diabetic foot patients: a nationwide population-based study. Diabetology & Metabolic Syndrome. 10:75. (SCI)
(20) Chern-Horng Lee, Chee-Jen Chang, Yu-Jr Lin, Cho-Li Yen, Chien-Heng Shen, Ya-Ting Cheng, Chen-Chun Lin, Sen-Yung Hsieh*. 2018,11. Nomogram predicting extrahepatic metastasis of hepatocellular carcinoma based on commonly available clinical data. JGH Open. 3(1):38-45.
(21) Chien-Te Ho, Ying‐Chang Tung, Shing‐Hsien Chou, Fu‐Chih Hsiao, Yu‐Sheng Lin, Chee‐Jen Chang, Pao‐Hsien Chu*, FCCP, FACC, FESC, FAPSC. 2018,12. Clinical outcomes in hypertensive patients treated with a single‐pill fixed‐dose combination of renin‐angiotensin system inhibitor and thiazide diuretic. J Clin Hypertens. 20(12):1731-1738. (SCI)
(22) Yu-Chih Lin*, Shen-Hsun Lee, I-Jung Chen, Chih-Hsiang Chang*, Chee-Jen Chang*, Yi-Chun Wang, Yuhan Chang, Pang-Hsin Hsieh*. 2018,12. Symptomatic pulmonary embolism following hip fracture: A nationwide study. Thrombosis Research. 172:120-127. (SCI)
(23) Yu-Chih Lin, Chih-Hsiang Chang, Chee-Jen Chang, Yi-Chun Wang, Pang-Hsin Hsieh, Yuhan Chang*. 2019,01. Vascular injury during primary total knee arthroplasty: A nationwide study. Journal of the Formosan Medical Association. 118:305-310. (SCI)
(24) Chyong-Huey Lai*, Elizabeth Vallikad, Hao Lin, Lan-Yan Yang, Shih-Ming Jung, Hsueh-Erh Liu, Yu-Che Ou, Hung-Hsueh Chou, Cheng-Tao Lin, Huei-Jean Huang, Kuan-Gen Huang, Jiantai Qiu, Yao-Ching Hung, Tzu-I Wu, Wei-Yang Chang, Kien-Thiam Tan, Chiao-Yun Lin, Angel Chao, Chee-Jen Chang. 2019,01. Maintenance of pegylated liposomal doxorubicin/carboplatin in patients with advanced ovarian cancer: randomized study of an Asian Gynecologic Oncology Group. Journal of Gynecologic Oncology. 31(1):e5. (SCI)
(25) Shih‐Chi Su, Chun‐Bing Chen, Wan‐Chun Chang, Chuang‐Wei Wang, Wen‐Lang Fan, Lai‐Ying Lu, Ryosuke Nakamura, Yoshiro Saito, Mayumi Ueta, Shigeru Kinoshita, Chonlaphat Sukasem, Kittika Yampayon, Pornpimol Kijsanayotin, Nontaya Nakkam, Niwat Saksit, Wichittra Tassaneeyakul, Michiko Aihara, Yu‐Jr Lin, Chee‐Jen Chang, Tony Wu, Shuen‐Iu Hung*, Wen‐Hung Chung*. 2019,02. HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians. Clinical Pharmacology and Therapeutics. 105(2):476-485. (SCI)
(26) Chun-Li Wang, Pei-Chun Chen, Hsiao-Ting Juang, Chee-Jen Chang*. 2019,04. Adverse Outcomes Associated with Pre-Existing and New-Onset Atrial Fibrillation in Patients with Acute Coronary Syndrome: A Retrospective Cohort Study. Cardiol Ther. 8(1):117-127.
(27) Hung-Yu Huang, Chun-Yu Lo, Lan-Yan Yang, Fu-Tsai Chung, Te-Fang Sheng, Horng-Chyuan Lin, Chang-Wei Lin, Yu-Chen Huang, Chee-Jen Chang, Kian Fan Chung, Chun-Hua Wang*. 2019,04. Maintenance Negative Pressure Ventilation Improves Survival in COPD Patients with Exercise Desaturation. J Clin Med. 8(4):562. (SCI)
(28) Alena Strizek*, Chee-Jen Chang, Wesley Furnback, Bruce Wang, Jérémie Lebrec, Thomas Lew. 2019,05. The Cost of Hypoglycemia Associated With Type 2 Diabetes Mellitus in Taiwan. Value in Health Regional Issues. 18:84-90.
(29) Chi-Hua Chen, Chun-Bing Chen, Chee Jen Chang, Yu Jr Lin, Chuang-Wei Wang, Ching-Chi Chi, Chun-Wei Lu, Wei-Ti Chen, Ren-You Pan, Shih-Chi Su, Lung-An Hsu, Ya-Ching Chang, Kuang-Hui Yu, Yeong-Jian Jan Wu, Ko-Ming Lin, Shuen-Iu Hung, Shin-Ming Chen*, Wen-Hung Chung*. 2019,08. Hypersensitivity and Cardiovascular Risks Related to Allopurinol and Febuxostat Therapy in Asians: A Population-Based Cohort Study and Meta-Analysis. Clinical Pharmacology and Therapeutics. 106(2):391-401. (SCI)
(30) Chia-Jui Yang, Hsiu-Yin Wang, Tse-Chih Chou, Chee-Jen Chang*. Prevalence and related drug cost of comorbidities in HIV-infected patients receiving highly active antiretroviral therapy in Taiwan: A cross-sectional study. 2019,10. Journal of Microbiology, Immunology and Infection. 52(5):720-727. (SCI)
(31) Dong-Yi Chen, Chen-Yu Li, Ming-Jer Hsieh, Chun-Chi Chen, I-Chang Hsieh, Tien-Hsing Chen, Shao-Wei Chen, Chao-Yung Wang, Shang-Hung Chang, Cheng-Hung Lee, Ming-Lung Tsai, Ming-Yun Ho, Jih-Kai Yeh, Chee-Jen Chang*, Ming-Shien Wen*. 2019,10. Predictors of subsequent myocardial infarction, stroke, and death in stable post-myocardial infarction patients: A nationwide cohort study. European Heart Journal: Acute Cardiovascular Care. 8(7):634-642
(32) Chia-Hsuan Tsai, Hsiang-Hao Hsu, Shih-Heng Chen, Ling Chien, Jennifer An-Jou Lin, Chee-Jen Chang*, Huang-Kai Kao*. 2020,01. Incidence and Risk of Carpal Tunnel Syndrome in End-Stage Renal Disease Patients on Dialysis: A Nationwide Population-Based Matched Cohort Study. Ann Plast Surg. 84(1S Suppl 1):S100-S106. (SCI)
(33) Hung-Yu Huang, Shih-Wei Lin, Li-Pang Chuang, Chih-Liang Wang, Ming-Hui Sun, Hsueh-Yu Li, Chee-Jen Chang, Shu-Chen Chang, Cheng-Ta Yang, Ning-Hung Chen*. 2020,07. Severe Obstructive Sleep Apnea Associated With Higher Risk of Mortality in Stage III and IV Lung Cancer. Journal of Clinical Sleep Medicin. 16(7):1091-1098. (SCI)
(34) Chun-Bing Chen, Tsun-Hao Hsu, Rosaline Chung-Yee Hui, Chun-Wei Lu, Wei-Ti Chen, Pin-Hsuan Chiang, Chuang-Wei Wang, Shiow-Shuh Chuang, Jui-Yung Yang, Shih-Yi Yang, Shu-Ying Chang, Yen-Chang Hsiao, Kuo-Chin Kao, Han-Chung Hu, Ting-Shu Wu, Chao-Wei Hsu, David Hui-Kang Ma, Shin-Yi Chen, Ya-Chung Tian, Chi-Yuan Cheng, Chi-Hua Chen, Min-Hui Chi, Ming-Ying Wu, Ren-Feng Liu, Chi-Hui Wang, Ya-Ching Chang, Jing-Yi Lin, Hsin-Chun Ho, Yang Yu-Wei Lin, Chee Jen Chang, Yu-Jr Lin, Cheng-Lung Ku, Shuen-Iu Hung, Wen-Hung Chung*, Taiwan Severe Cutaneous Adverse Reaction Consortium. 2020,08. Disseminated intravascular coagulation in Stevens-Johnson syndrome and toxic epidermal necrolysis. J Am Acad Dermatol. 84(6):1782-1791. (SCI)
(35) Hsien-Yi Chiu, Chee Jen Chang, Yu Jr Lin, Tsen-Fang Tsai*. 2020,09. National trends in incidence, mortality, hospitalizations, and expenditures for pemphigus in Taiwan. Journal of Dermatological Science. 99(3):203-208. (SCI)
(36) Tzu-Yu Lin, Chi-Yuan Cheng, Yi-Chia Chen, Shu-Chen Chang, Chi-Hua Chen*, Chee-Jen Chang. 2020,10. The cancer-specific survival benefit of adjuvant chemotherapy for patients aged 75 or older with stage III colon cancer. Formosa Journal of Clinical Pharmacy. 28(4):320-334.
(37) Chih-Hsiang Chang, Sheng-Hsun Lee, Yu-Chih Lin, Yi-Chun Wang, Chee-Jen Chang, Pang-Hsin Hsieh*. 2020,11. Increased periprosthetic hip and knee infection projected from 2014 to 2035 in Taiwan. Journal of Infection and Public Health. 13(11):1768-1773. (SCI)
(38) Chih-Hsiang Chang, Chee-Jen Chang, Yi-Chun Wang, Chih-Chien Hu, Yuhan Chang, Pang-Hsin Hsieh, Dave W Chen*. 2020,9-12. Increased incidence, morbidity, and mortality in cirrhotic patients with hip fractures: A nationwide population-based study. J Orthop Surg (Hong Kong). 28(3):2309499020918032. (SCI)
(39) Shih-Chiang Huang, Kwai-Fong Ng, Ian Yi-Feng Chang, Chee-Jen Chang, Yi-Chun Chao, Shu-Chen Chang, Min-Chi Chen, Ta-Sen Yeh, Tse-Ching Chen*. 2021,01. The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes. PLOS ONE. 16(1):e0245356. (SCI)
(40) Chun-Bing Chen, Kang-Ling Kuo, Chuang-Wei Wang, Chun-Wei Lu, Rosaline Chung-Yee Hui, Kun-Lin Lu, Wan-Chun Chang, Wei-Ti Chen, Fu Yun, Yu-Chuan Teng, Hua-En Lee, Jing-Yi Lin, Hsin-Chun Ho, Min-Hui Chi, Yang Yu-Wei Lin, Chee Jen Chang, Yu Lin Jr, Cheng-Lung Ku, Shuen-Iu Hung, Ya-Ching Chang, Wen-Hung Chung*, Taiwan Severe Cutaneous Adverse Reaction Consortium. 2021,03. Detecting Lesional Granulysin Levels for Rapid Diagnosis of Cytotoxic T lymphocyte-Mediated Bullous Skin Disorders. J Allergy Clin Immunol Pract. 9(3):1327-1337.e3. (SCI)
(41) Shyue-Luen Chang, Sindy Hu, Yau-Li Huang, Mei-Ching Lee, Wen-Hung Chung, Chun-Yu Cheng, Yen-Chang Hsiao, Chee Jen Chang, Shu Ru Lee, Su-Wei Chang, Yu-Wen Wen*. 2021,03. Treatment of Varicose Veins Affects the Incidences of Venous Thromboembolism and Peripheral Artery Disease. Circ Cardiovasc Interv. 14(3):e010207. (SCI)
(42) Chen CB, Chen YE, Chu MT, Wang CW, Hui RC, Lu CW, Hsiao YP, Chu CY, Chang MM, Cheung CM, Cheng CY, Wang YW, Lin YJ, Chang CJ, Hung SI*, Chung WH*, Taiwan Severe Cutaneous Adverse Reaction Consortium. 2021,03. The risk of anti-osteoporotic agent-induced severe cutaneous adverse drug reactions and their association with HLA. J Eur Acad Dermatol Venereol. 35(3):712-720. (SCI)
(43) Li-Chung Chiu, Li-Pang Chuang, Shaw-Woei Leu, Yu-Jr Lin, Chee-Jen Chang, Hsin-Hsien Li, Feng-Chun Tsai, Chih-Hao Chang, Chen-Yiu Hung, Shih-Wei Lin, Han-Chung Hu, Chung-Chi Huang, Huang-Pin Wu, Kuo-Chin Kao*. 2021,03. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome: Propensity Score Matching. Membranes. 11(6):393. (SCI)
(44) Chuang-Wei Wang, Wichittra Tassaneeyakul, Chun-Bing Chen, Wei-Ti Chen, Yu-Chuan Teng, Cheng-Yang Huang, Chonlaphat Sukasem, Chun-Wei Lu, Yun-Shien Lee, Siew-Eng Choon, Nontaya Nakkam, Rosaline Chung-Yee Hui, Yen-Hua Huang, Ya-Ching Chang, Yang Yu-Wei Lin, Chee-Jen Chang, Tsu-Man Chiu, Wasun Chantratita, Parinya Konyoung, Chaw-Ning Lee, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Warayuwadee Amornpinyo, Niwat Saksit, Pawinee Rerknimitr, Huang Yu Huei, Shang-Hong Lin, Chao-Kai Hsu, Wen-Lang Fan, Cheng-Chi Chan, Yu-Jr Lin, Shuen-Iu Hung*, Wen-Hung Chung*, Taiwan/Asian Severe Cutaneous Adverse Reaction Consortium. 2021,04. Whole Genome Sequencing Identifies Genetic Variants Associated with Co-trimoxazole Hypersensitivity in Asians. Journal of Allergy and Clinical Immunology. 147(4):1402-1412. (SCI)
(45) Jui-Fan Chiang, Ming-Hui Sun*, Kuan-Jen Chen, Wei-Chi Wu, Chi-Chun Lai, Chee-Jen Chang, Yu-Jr Lin, Shu-Chen Chang, Hung-Yu Huang, Ning-Hung Chen, Hsueh-Yu Li. 2021,06. Association between obstructive sleep apnea and diabetic macular edema in patients with type 2 diabetes. Am J Ophthalmol. 226:217-225. (SCI)
(46) Chih-Kuo Lee, Tzung-Dau Wang*, Hsiao-Ting Juang, Shu-Chen Chang, Heng-Yu Pan, Donna Shu-Han Lin, Chee-Jen Chang*. 2021,07. Efficacy and safety of ticagrelor versus clopidogrel in patients with non-ST-elevation myocardial infarction in Taiwan. Scientific Reports. 11:14150. (SCI)
(47) Hung-Yu Huang, Chee-Jen Chang, Shu-Chen Chang, Li-Fu Li*. 2021,08. Author Reply to letter to the editor "clinical outcomes and prognostic factors for prolonged mechanical ventilation in patients with acute stroke and brain trauma". J Formos Med Assoc. 120(8):1658-1659. (SCI)
(48) Sheng-Hsun Lee,Yu-Chih Lin, Chee-Jen Chang, Chih-Yun Fan Chiang, Szu-Yuan Chen, Yu-Han Chang, Pang-Hsin Hsieh, Chih-Hsiang Chang*. 2021,10. Outcome and Cost Analysis of Primary Total Knee Arthroplasty in End-stage Renal Disease Patients: A Nationwide Population-based Study. Biomed J. 44(5):620-626. (SCI)
(49) Hung-Yu Huang, Chung-Shu Lee, Tzu-Hsuan Chiu, Hsiang Hsuan Chen, Li-Yi Chan, Chee-Jen Chang, Shu-Chen Chang, Han-Chung Hu, Kuo-Chin Kao, Ning-Hung Chen, Shu-Min Lin, Li-Fu Li*. 2022,01. Clinical outcomes and prognostic factors for prolonged mechanical ventilation in patients with acute stroke and brain trauma. J. Formos. Med. Assoc. 121(1 Pt 1):162-169. (SCI)
18.monograph & Book Papers
(1) Kenneth K. C. Lee, Wai Yee Choon, Chee Jen Chang, Jeff Guo and Paul Scuffham. (2022). Increasing Importance of Patients-generated Real World Data for Healthcare Policy Decisions about Medicinal Products. Frontiers in Pharmacology.